First human trial of a vaccine to protect against COVID-19 began in the US

The vaccine contains a harmless genetic code copied from the virus that causes the disease. It cannot cause COVID-19.
Sudha

Updated: Mar 17,2020 12:06:01 pm

First human trial of a vaccine to protect against COVID-19 began in the US

17 March 2020 Current Affairs:The first human trial of a vaccine against coronavirus (COVID-19) began at Kaiser Permanente Washington Health Research Institute (KPWHRI) in Seattle, the US. 

Covid-19 vaccine trial:
♦ The vaccine is called mRNA-1273. The vaccine has shown promise in animal models.
♦ It was developed by NIAID scientists and their collaborators at the biotechnology company Moderna, Inc., based in Cambridge, Massachusetts. 
♦ A 43-year-old woman from Seattle received the first dose. 
♦ The vaccine contains a harmless genetic code copied from the virus that causes the disease. It cannot cause COVID-19.
♦ The trial will enroll 45 healthy adult volunteers over approximately six weeks.
♦ The Coalition for Epidemic Preparedness Innovations (CEPI) supported the manufacturing of the vaccine candidate for the Phase 1 clinical trial.
♦ The study participants will receive two doses of the vaccine via intramuscular injection in the upper arm approximately 28 days apart.
♦ Participants will return to the clinic for follow-up visits between vaccinations and for additional visits across the span of a year after the second shot. 
♦ The participants will be monitored by the Clinicians for common vaccination symptoms, such as soreness at the injection site or fever, as well as any other medical issues. 
♦ A safety monitoring committee will also periodically review trial data and advise NIAID.
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